Hypertension is the most common comorbidity of obesity, which is corrected in up to 66% of patients who lose excess weight.
The risk of coronary artery disease is also higher in the obese population.
Venous stasis disease with significant chronic morbidity.
Endocrine
These patients have an increased incidence of non-insulin-dependent diabetes mellitus.
Adipose tissue acts as an endocrine organ; adipocytes secrete enzymes important in sex steroid and glucocoarticoid metabolism, resulting in excessive levels of androstenedione and estradiol. The hormones lead to feminization in men and masculinization, polycystic ovarian disease, amenorrhea, and infertility in women in women.
Pulmonary
The incidence of obstructive sleep apnea is 12 to 30-fold higher in the morbidly obese than in the general population.
Cancer
Cancer mortality rates are increased in the morbidly obese compared with the general population.
Mortality rates for obese women are increased for endometrial, gallbladder, uterine, cervix, ovarian, and breast cancers.
Mortality rates for obese men are increased for colorectal and prostate cancers.
